12 May 2023

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Insomnia associated with symptoms of central sensitization in patients with painful temporomandibular disorders

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Background

Central sensitization (CS) and temporomandibular disorder (TMD) are both associated with insomnia. Therefore, the authors aimed to investigate whether insomnia was associated with more symptoms of CS in patients with TMD.

Methods

In 82 volunteers with TMD, insomnia was clinically assessed, allowing sample stratification according to its presence. The Central Sensitization Inventory questionnaire was self-applied to assess the clinical symptoms of CS.

Results

Participants with insomnia had significantly higher mean (SD) scores of CS according to the Central Sensitization Inventory than participants without insomnia (43.10 [12.57] vs 26.59 [13.66]; P = < .001).

Conclusions

Insomnia was associated with higher scores of CS symptoms in patients with TMD.

Practical implications

Insomnia influences TMD as well as its relationship with CS, and, therefore, it is critical to the clinical management of TMD.

Fernanda Grüninger Mercante et al. "Insomnia is associated with symptoms of central sensitization in patients with painful temporomandibular disorders." JADA. 20 April 2023. DOI:https://doi.org/10.1016/j.adaj.2023.02.017