Rehabilitation with removable dentures is considered the cheapest and most common treatment for restoring oral function in edentulous patients.
Well-fitting and correctly positioned removable full dentures have a positive impact on both functional and psychological aspects, well-being and quality of life of patients. However, the conditions for guaranteeing the stability of mobile prostheses, retention and adequate comfort do not always exist, leading dentists to prescribe adhesives for prosthesis wearers.
Denture adhesives can also provide reassurance and comfort to the patient, particularly during public interaction occasions. They can improve chewing quality, reduce food debris build-up under the denture and offer a cushioning effect by decreasing pressure and friction transmitted by the prosthesis to the underlying mucosa.
Furthermore, denture adhesives can have an antimicrobial activity thanks to components such as hexachlorophene, ethanol and methyl salicylate. These antimicrobial agents have demonstrated limited action against Candida albicans, a microorganism strongly associated with denture stomatitis.
Materials and methods
In a study published in April 2023 in the Journal of Dentistry, the authors evaluated the antimicrobial potential of silver nanoparticles (Ag NPs) synthesized by three methods, incorporated into denture powder adhesive (Corega).
Samples of heat cured acrylic resin were treated with several types of Ag NP associated with the adhesive according to the following groups
Results
The results of this study revealed an inhibition of the fungal load and a reduction of the metabolic activity and of the biofilm mass in the resin samples treated with the AD/Ag NP combinations, compared to the AD and control groups. PBS extension. The antimicrobial action of the AD + Turk and AD + Ag Gm groups was similar to that of the AD + Nyst group in all periods and for all variables evaluated except for the biofilm mass (12 h).
Conclusions
From the data of this study, researchers concluded that denture adhesive containing silver nanoparticles Ag NPs (mainly those synthesized using Turkevich and Glycine max methods) show excellent antimicrobial activity against biofilm of C. albicans, antimicrobial activity that lasts up to 12 hours.
The association of Ag NPs to the adhesive can add preventive or therapeutic effects against denture stomatitis to this prosthetic material.
For more information: "Silver nanoparticles in denture adhesive: An antimicrobial approach against Candida albicans."
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