14 May 2025

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Prosthodontic rehabilitation of oral function in head–neck cancer patients with dental implants placed simultaneously during ablative tumour surgery: an assessment of treatment outcomes and quality of life

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The aim of this prospective study was to assess treatment outcome and impact on quality of life of prosthodontic rehabilitation with implant-retained prostheses in head–neck cancer patients.

Fifty patients were evaluated by standardized questionnaires and clinical assessment. All received the implants during ablative tumour surgery in native bone in the interforaminal area. About two-thirds of the patients (n = 31) needed radiotherapy post-surgery. Both in irradiated and non-irradiated bone two implants were lost 18–24 months after installation. Peri-implant tissues had a healthy appearance. No cases of osteoradionecrosis occurred.

In 15 patients no functional implant-retained lower dentures could be made for various reasons. The other 35 patients all functioned well, with an improvement in quality of life. Major improvement was observed in the non-irradiated patients. In the irradiated patients, less improvement in many functional items was observed, while items related to the oral sequelae of radiotherapy did not improve.

Similar to the quality-of-life assessments, denture satisfaction was improved and tended to be higher in non-irradiated than irradiated patients. Implant-retained lower dentures can substantially improve the quality of life related to oral functioning and denture satisfaction in head–neck cancer patients. This effect is greater in non-irradiated than irradiated cancer patients.

Authors: P.J. Schoen, M. Raghoebar, J. Bouma, H. Reintsema, F.R. Burlage, J.L.N. Roodenburg, A. Vissink

Source: https://www.sciencedirect.com/