Patient-centered trial design improves recruitment and retention, increases participant satisfaction, encourages participation by a more representative cohort and allows researchers to better meet...
How to interpret the magnitude of clinical study results
In the oral health literature, researchers sometimes report measures of association that are inappropriate for their study design.
Researchers examined the plaque removal effectiveness of a personalized 3D-printed dental plaque removal mouthguard device in a clinical trial.
One of the problems that orthodontists commonly face is the prolonged duration of the treatment. Therefore, it is important to find an effective method to increase the rate of orthodontic tooth...
Clinical trials 02 May 2023
In this double-blind randomized clinical trial study, 60 female patients between the ages of 14 and 30 years who had moderate tooth crowding and were candidates for fixed orthodontic treatment were...
A newly drafted report by the National Toxicology program (NTP) has removed the hazard classification of fluoride.
This study answered the research question “Is the risk of tooth sensitivity lower when calcium-containing bioactive desensitizers are used with dental bleaching in adults compared with...
Clinical trials 03 February 2023
Global attitudes towards open data
The 2022 State of Open Data report shows a growing consensus that data produced by researchers should be made openly available. But clear challenges remain.
Researchers conducted a randomized clinical trial in adult patients with TMJ subluxation, including those with painful open locking or yawning at baseline. ...
Clinical trials 21 September 2022
Chewing gum that may block SARS-CoV-2 moves to clinical trial
A recently launched clinical trial at the University of Pennsylvania will evaluate a novel chewing gum designed by Penn Dental Medicine’s Henry Daniell, W.D. Miller Professor in the Department of...