Introduction
This study aimed to evaluate the use of deep convolutional neural network (DCNN) algorithms to detect clinical features and predict the three-year outcome of endodontic treatment on preoperative periapical radiographs.
Methods
A database of single-root premolars that received endodontic treatment or retreatment by endodontists with presence of three-year outcome was prepared (n = 598). Researchers constructed a 17-layered DCNN with a self-attention layer (Periapical Radiograph Explanatory System with Self-Attention Network [PRESSAN-17]), and the model was trained, validated, and tested to 1) detect 7 clinical features, that is, full coverage restoration, presence of proximal teeth, coronal defect, root rest, canal visibility, previous root filling, and periapical radiolucency and 2) predict the three-year endodontic prognosis by analyzing preoperative periapical radiographs as an input.
During the prognostication test, a conventional DCNN without a self-attention layer was tested for comparison. Accuracy and area under the receiver-operating-characteristic curve were mainly evaluated for performance comparison. Gradient-weighted class activation mapping was used to visualize weighted heatmaps.
Results
PRESSAN-17 detected full coverage restoration (area under the receiver-operating-characteristic curve = 0.975), presence of proximal teeth (0.866), coronal defect (0.672), root rest (0.989), previous root filling (0.879), and periapical radiolucency (0.690) significantly, compared to the no-information rate (P < .05).
Comparing the mean accuracy of 5-fold validation of 2 models, PRESSAN-17 (67.0%) showed a significant difference to RESNET-18 (63.4%, P < .05). Also, the area under average receiver-operating-characteristic of PRESSAN-17 was 0.638, which was significantly different compared to the no-information rate. Gradient-weighted class activation mapping demonstrated that PRESSAN-17 correctly identified clinical features.
Conclusions
Deep convolutional neural networks can detect several clinical features in periapical radiographs accurately. Based on our findings, well-developed artificial intelligence can support clinical decisions related to endodontic treatments in dentists.
Junghoon Lee et al. "An Endodontic Forecasting Model Based on the Analysis of Preoperative Dental Radiographs: A Pilot Study on an Endodontic Predictive Deep Neural Network." Journal of Endodontics. 4 April 2023. DOI: https://doi.org/10.1016/j.joen.2023.03.015
Artificial intelligence (AI) is the development of computer systems whereby machines can mimic human actions. This is increasingly used as an assistive tool to help clinicians diagnose and treat...
Endodontics 01 September 2025
Many recent technological advancements have been made in the field of endodontics; however, comparatively few studies have evaluated their impact on tooth survival.
Endodontics 18 August 2025
Factors influencing the long-term results of endodontic treatment: a review of the literature
The purpose of this review of the literature is to examine the factors and their influence on the outcome of endodontic treatments, and also to attempt to have an authors’ consensus concerning the...
Endodontics 27 February 2025
Apical extrusion of infected debris to the periradicular tissues is one of the principal causes of postoperative pain and discomfort.
Endodontics 12 February 2025
Evaluation of the Role of Probiotics in Endodontic Treatment
The principal goal of endodontics is the prevention of periapical infection. Acute and chronic apical periodontitis occur due to the persistence of pathogenic microorganisms such as Enterococcus...
News 23 April 2026
Personify Group, a strategic branding, communications, and growth advisory firm serving the dental industry, announced today that Mason Kesner, a B2B/B2C commer
News 23 April 2026
Two-day event in Broomfield, Colorado, brings dental, medical and behavioral health professionals together for hands-on collaboration The American Dental Hygien
Prevention of dental caries and periodontal disease for people with special needs is a challenging problem in dentistry.
The new clinic and education center is planned to open this fall, and it will position Temple as a leader when it comes to addressing rural healthcare challenges.