The clinical and radiographic effectiveness of 38% silver diamine fluoride (SDF) with and without potassium iodide (KI) was tested and compared with resin-modified glass ionomer cement (RMGIC) in indirect pulp capping of deep carious lesions in young permanent molars.
Methods
One hundred eight permanent first molars with deep occlusal cavitated carious lesions in 49 children aged six through nine years were randomly allocated into three groups (n = 36 molars per group) and treated with SDF plus KI, SDF and RMGIC.
RMGIC was used as a base and a resin-based composite restoration followed. Clinical assessments for secondary caries (primary outcome), postoperative pain, tooth vitality and restoration success and quality rates according to Modified U.S. Public Health Service and Ryge Criteria for Direct Clinical Evaluation of Restorations were performed after three, six and 12 months. Periapical radiographs were obtained at baseline, six and 12 months. Outcomes were assessed using mixed effects multilevel logistic and linear regression analyses.
Results
There were no significant differences (P = .26) among the groups for secondary caries, postoperative pain, tooth vitality, clinical abscess, radiographic signs of pulpal pathology, restorations’ marginal adaption, anatomic form and surface roughness. There was a significant difference (P = .03) in restoration color, marginal staining and luster. The RMGIC group outperformed the two SDF groups in color and luster.
Conclusions
The authors did not find differences among the groups in preventing secondary caries or pain or in maintaining pulpal health. The RMGIC group had better restoration color and luster than both SDF groups and better marginal staining than the SDF group.
Practical Implications
The results of this study can help guide treatment decision making regarding use of SDF and SDF plus KI as indirect pulp capping materials in deep cavitated lesions.
Baraka, Marwa et al. JADA. “Twelve-month randomized controlled trial of 38% silver diamine fluoride with or without potassium iodide in indirect pulp capping of young permanent molars.” JADA. October 14, 2022 DOI: https://doi.org/10.1016/j.adaj.2022.08.008
Pediatric dentistry 28 February 2023
CariedAway school-based trial prevented 80% of cavities with non-invasive treatment
A single dose of either of the two topical treatments administered in elementary schools prevented about 80% of cavities and 50% of cavities from worsening.
Pediatric dentistry 01 February 2023
Researchers hypothesized that SDF was superior to FV at one year. Secondary objectives were to determine the child's cooperation and the parent's satisfaction and assess adverse effects.
Market 04 November 2022
New CPT code allows clinicians to apply silver diamine fluoride to treat cavities
The American Medical Association approved a new category III CPT code for the application of silver diamine fluoride by medical teams to arrest dental decay...
In the clinical practice of a dentist, it often happens that you must re-operate on restorations performed in the past and often the most common causes can be traced back to secondary caries,...
Restorative dentistry 01 November 2022
Dental restorative materials with sustained antibacterial action
Dental restorative materials with antibacterial properties can potentially solve secondary caries that occur around restorations.
Products 02 June 2026
ETNA Rotary Instruments From Komet USA Well Suited for Zirconia and Ceramic Restorations
ETNA rotary instruments is a high-performance system of abrasive stones and 2-step polishers designed for zirconia and ceramic restorations.
News 02 June 2026
New humorous “Close the Gap” campaign highlights how same-day dentistry is making it possible to restore missing teeth in minutes
News 02 June 2026
Himed , a pioneering producer of bioceramic materials, and Adva Cera , a leader in advanced ceramic additive manufacturing, today announced a strategic partnership to create a comp
The forerunner of what’s now Texas A&M College of Dentistry opened 120 years ago in Dallas with the mission of educating dentists to provide quality care to patients in North Texas
Oral pathology 02 June 2026
This peer-reviewed oral pathology article summarizes clinical evidence from Oral oncology (2026). It focuses on findings that may help dental professionals evaluate treatment decisions, patient...