21 October 2026

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Effect of continuous wave of condensation on postoperative pain using bioceramic versus resin sealers: a randomized clinical trial.

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This peer-reviewed endodontics article summarizes clinical evidence from BMC oral health (2026). It focuses on findings that may help dental professionals evaluate treatment decisions, patient outcomes, or clinical protocols.

Abstract

BACKGROUND: The clinical behavior of bioceramic sealers under heat-based obturation techniques remains insufficiently explored, despite their widespread clinical use. Although these materials are generally recommended for single-cone techniques, their performance when exposed to heat during warm obturation procedures is still controversial. This randomized clinical trial aimed to evaluate postoperative pain following the use of bioceramic and epoxy resin-based sealers in combination with the continuous wave of condensation technique (CWCT), addressing a clinically relevant gap in the literature.

METHODS: Seventy-two patients with single-rooted teeth diagnosed with asymptomatic irreversible pulpitis were randomly assigned to three groups (n = 24): AH Plus, TotalFill BC Sealer, and Bio-C Sealer. All treatments, including post-endodontic restorations, were completed in a single visit by a single experienced operator using the CWCT. Postoperative pain intensity was assessed using a visual analog scale (VAS; 0-10), and pain incidence was recorded at 6, 24, 48, and 72 h, and 7 days. Statistical analyses included Fisher's exact test with Monte Carlo simulation, Cochran's Q test, and binary logistic regression analysis (α = 0.05).

RESULTS: No statistically significant differences were observed among the three sealer groups regarding postoperative pain incidence or intensity at any time point (P > 0.05). Pain incidence was highest within the first 24 h (16.7% at 6 h and 11.1% at 24 h) and decreased significantly over time (P < 0.001), with complete resolution after 48 h. None of the evaluated variables, including age, gender, jaw, or sealer type, significantly influenced postoperative pain outcomes.

CONCLUSION: No significant difference in short-term postoperative pain was detected among the three root canal sealers when used with the continuous wave of condensation technique.

TRIAL REGISTRATION: ClinicalTrials.gov NCT06726837, 10 December 2024.

Key takeaway

Key takeaway: Because the evidence comes from a clinical trial design, the findings may be especially useful when comparing treatment approaches in daily practice.

Introduction from full text

Evaluating the effect of different obturation techniques on postoperative pain level and radiographic healing on non-surgical endodontic retreatment (NSER) applied in a single visit in teeth with a single root canal and apical periodontitis (AP).

Peer-reviewed source

Merve Defişet, Merve Yeniçeri Özata

BMC oral health. 2026

DOI: 10.1016/j.archoralbio.2022.105371

PMID: 42426769

PubMed: https://pubmed.ncbi.nlm.nih.gov/42426769/

Image: Ozkan Guner (Unsplash)